They shall take up serpents; and if they drink any deadly thing, it shall not hurt them; they shall lay hands on the sick, and they shall recover.
These words appear at the end of the Gospel of Mark, where Jesus — after his resurrection — commissions his followers to go into the world and proclaim his message. The signs he describes (handling snakes, surviving poison, healing the sick) are presented as evidence that God will be with those who carry the gospel into dangerous territory. This is one of the more debated passages in the Bible for two reasons: many early manuscripts don't include this section of Mark at all, making scholars uncertain whether it was part of the original text; and some Christian communities have taken this verse literally (snake-handling churches exist today in parts of Appalachia), while most understand it as a promise of divine protection for messengers facing real danger, not a prescribed practice.
Lord, you sent ordinary, frightened people to do impossible things and promised to be with them. I don't need to handle snakes — but I do need a courage I don't naturally have. Be present with me in the risky and honest moments that come with following you. Amen.
Let's be honest — this might be the most uncomfortable verse you'll sit with in a devotional. Snakes. Poison. Bare hands. It sounds less like spiritual encouragement and more like a dare. But zoom out: Jesus is sending ordinary, frightened people into a world that would torture and kill them for what they were about to say. He's not handing them a self-improvement program. He's promising that nothing — not venom, not violence, not the worst the world can organize against them — will stop what he's set in motion. The signs aren't about showmanship. They're about the unstoppability of the message. Most of us won't face literal snakes. But we do face the specific fear of saying something true when it costs something. The conversation you've been avoiding. The part of your faith you keep private because you're not sure how people will react. The stand you haven't taken because the room might go cold. Jesus' promise here isn't immunity from discomfort — it's presence inside it. What is the risky, honest thing you've been carrying quietly, waiting for a safer moment that may not come?
How do you personally interpret this verse — as a literal promise to all believers, a description of early church experience, or something else? What shapes that reading for you?
Have you ever experienced a moment in your faith where you felt unexpectedly protected or sustained in a situation that seemed too hard to bear alone?
This passage is genuinely contested — some early manuscripts don't include it, and Christians disagree about its meaning. How do you hold that kind of biblical uncertainty without it undermining your broader faith?
If the deeper point is courage in the face of real risk, where in your relationships are you currently playing it safe when honesty is what's actually needed?
What is one risky, honest, or courageous step in your faith that you've been postponing? What would it take to stop waiting?
And Peter said unto him, Aeneas, Jesus Christ maketh thee whole: arise, and make thy bed. And he arose immediately.
Acts 9:34
Is any sick among you? let him call for the elders of the church; and let them pray over him, anointing him with oil in the name of the Lord:
James 5:14
Behold, I give unto you power to tread on serpents and scorpions, and over all the power of the enemy: and nothing shall by any means hurt you.
Luke 10:19
And his name through faith in his name hath made this man strong, whom ye see and know: yea, the faith which is by him hath given him this perfect soundness in the presence of you all.
Acts 3:16
By stretching forth thine hand to heal; and that signs and wonders may be done by the name of thy holy child Jesus.
Acts 4:30
And the prayer of faith shall save the sick, and the Lord shall raise him up; and if he have committed sins, they shall be forgiven him.
James 5:15
Then he called his twelve disciples together, and gave them power and authority over all devils, and to cure diseases.
Luke 9:1
And the God of peace shall bruise Satan under your feet shortly . The grace of our Lord Jesus Christ be with you. Amen.
Romans 16:20
they will pick up serpents, and if they drink anything deadly, it will not hurt them; they will lay hands on the sick, and they will get well."
AMP
they will pick up serpents with their hands; and if they drink any deadly poison, it will not hurt them; they will lay their hands on the sick, and they will recover.”
ESV
they will pick up serpents, and if they drink any deadly [poison], it will not hurt them; they will lay hands on the sick, and they will recover.'
NASB
they will pick up snakes with their hands; and when they drink deadly poison, it will not hurt them at all; they will place their hands on sick people, and they will get well.”
NIV
they will take up serpents; and if they drink anything deadly, it will by no means hurt them; they will lay hands on the sick, and they will recover.”
NKJV
They will be able to handle snakes with safety, and if they drink anything poisonous, it won’t hurt them. They will be able to place their hands on the sick, and they will be healed.”
NLT
they will take snakes in their hands, they will drink poison and not be hurt, they will lay hands on the sick and make them well."
MSG